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A prolyl oligopeptidase inhibitor, KYP-2047, reduces α-synuclein protein levels and aggregates in cellular and animal models of Parkinson’s disease.

A prolyl oligopeptidase inhibitor, KYP-2047, reduces α-synuclein protein levels and aggregates in cellular and animal models of Parkinson’s disease. Br J Pharmacol. 2012 Jan 10; Authors: Myöhänen TT, Hannula MJ, Van Elzen… [...]

New pharmacological avenues for the treatment of l-DOPA-induced dyskinesias in Parkinson’s disease: targeting glutamate and adenosine receptors.

New pharmacological avenues for the treatment of l-DOPA-induced dyskinesias in Parkinson’s disease: targeting glutamate and adenosine receptors. Expert Opin Investig Drugs. 2012 Jan 11; Authors: Blandini F, Armentero MT … [...]

Progression of motor symptoms in Parkinson’s disease.

Progression of motor symptoms in Parkinson’s disease. Neurosci Bull. 2012 Feb;28(1):39-48 Authors: Xia R, Mao ZH Abstract Parkinson’s disease (PD) is a chronic progressive neurodegenerative disease that is cl… [...]

Apathy in parkinson’s disease: Diagnostic and etiological dilemmas.

Apathy in parkinson’s disease: Diagnostic and etiological dilemmas. Mov Disord. 2012 Jan 11; Authors: Starkstein SE Abstract About one-third of patients with Parkinson’s disease (PD) are diagnosed with apathy… [...]

Abnormal Activity in the Precuneus during Time Perception in Parkinson’s Disease: An fMRI Study.

Abnormal Activity in the Precuneus during Time Perception in Parkinson’s Disease: An fMRI Study. PLoS One. 2012;7(1):e29635 Authors: Dušek P, Jech R, Sieger T, Vymazal J, Růžička E, Wackermann J, Mueller K Abstra… [...]